Reserch

High-quality single crystal growth of DNA-functionalized nanoparticles

High-crystallinity Nano-gapped Particle Superlattice was assembled via DNA-guided Colloidal Crystallization and isotropic dehydration contraction.

Nanoparticle superlattice assembled by DNA-guided colloidal crystallization

Development of structural analysis method using small angle X-ray scattering

We are developing a method for single crystal structure analysis of crystals with periodic structures in the nano- to meso-scale by combining small-angle X-ray scattering and rotational crystal methods. By analyzing the internal structure of a single crystal in detail, we are optimizing the conditions for assembling high-quality single crystals. 

Lipid-bilayer-assisted two-dimensional self-assembly of DNA-functionalized nanoparticles

Due to the in-plane fluidity of lipid bilayers, we have succeeded in two-dimensional crystallization of DNA-functionalized nanoparticles and control of their structure. The structure can be controlled by changing the type and concentration of ions.

DNA-NP assembly on Supported lipid bilayer:
particle formation change by cationic ions

Self-assembly of porous nanoparticle superlattices and molecular encapsulation

Porous DNA-functionalized nanoparticle superlattice, that can encapsulate protein molecules and nanomaterials simply by mixing, have been successfully assembled. The application to carriers for drug delivery system is expected.